Clinical Best Practices

Clinical Best Practices

Top 10 Infection Control Best Practices for Healthcare Facilities

Evidence-based infection control practices that every healthcare facility should implement. Learn the strategies that reduce hospital-acquired infections and improve patient outcomes.

By Admin User
October 23, 2025
12 min read
Infection ControlBest PracticesPatient SafetyHealthcare Quality

Healthcare-associated infections (HAIs) affect 1 in 31 hospital patients on any given day. Implementing robust infection control practices is essential for patient safety and quality care.

1. Hand Hygiene Compliance

Hand hygiene is the single most effective way to prevent infection transmission. The WHO "5 Moments for Hand Hygiene" provides a framework:

Before touching a patient
Before clean/aseptic procedures
After body fluid exposure risk
After touching a patient
After touching patient surroundings

Implementation tip: Place alcohol-based hand sanitizer dispensers at every point of care. Studies show that easy accessibility increases compliance by 40%.

2. Standard and Transmission-Based Precautions

Standard precautions should be used for all patients, all the time. This includes:

Hand hygiene
PPE use based on anticipated exposure
Safe injection practices
Safe handling of potentially contaminated equipment

3. Environmental Cleaning and Disinfection

High-touch surfaces should be cleaned and disinfected at least daily, and more frequently in high-risk areas. Focus on:

Bed rails and overbed tables
Light switches and door handles
IV poles and infusion pumps
Computer keyboards and phones

4. Antimicrobial Stewardship

Appropriate antibiotic use prevents resistance and reduces C. difficile infections. Key strategies include:

Culture-guided therapy
Shortest effective duration
De-escalation when appropriate
IV to oral conversion

5. Central Line-Associated Bloodstream Infection (CLABSI) Prevention

Bundle approach includes:

Hand hygiene before insertion
Maximal barrier precautions
Chlorhexidine skin antisepsis
Optimal catheter site selection
Daily review of line necessity

6. Catheter-Associated Urinary Tract Infection (CAUTI) Prevention

Reduce urinary catheter use and ensure proper maintenance:

Insert only when medically necessary
Remove as soon as possible
Maintain closed drainage system
Position drainage bag below bladder

7. Surgical Site Infection (SSI) Prevention

Multimodal approach:

Appropriate prophylactic antibiotics within 1 hour of incision
Hair removal with clippers, not razors
Maintain perioperative normothermia
Glycemic control in cardiac surgery patients

8. Respiratory Hygiene/Cough Etiquette

Implement measures to contain respiratory secretions:

Post visual alerts at entry points
Provide tissues and no-touch waste receptacles
Offer masks to coughing patients
Ensure hand hygiene after contact with respiratory secretions

9. Staff Education and Training

Ongoing education is crucial. Implement:

Annual competency assessments
Regular safety huddles
Just-in-time training for new procedures
Simulation-based training for high-risk procedures

10. Surveillance and Feedback

Monitor infection rates and provide regular feedback to staff:

Track HAI rates by unit and procedure
Share data with frontline staff monthly
Celebrate successes and address challenges
Benchmark against national standards

Implementing these evidence-based practices creates a culture of safety that protects both patients and healthcare workers. Success requires leadership commitment, staff engagement, and continuous improvement.

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